Determination of levels of Transferase enzymes, Alkaline phosphatase, Cholesterol and Bilirubin, associated with hepatic disturbances in patients presented to laboratories in Baquba-City

Abstract

This cross–sectional study included 200 individuals, 15 males of one year, 25 females of one to 5 years old, 100 males of 10-73 years, and 60 females of 15-73 years, presented to official and private laboratories in Baqubah - City, during the 2023 year. Blood samples were collected upon which some biochemical constituents related to hepatic disturbances were determined, including transferase enzymes, serum bilirubin, serum alkaline phosphatase, cholesterol, serum total protein, albumin, urea nitrogen, and creatinine. The results showed that mean values of alanine aminotransferase were high in young males, and adult males, and females, the highest was in adult males. There is significant variance between young and adults and between males and females. The mean of aspartate aminotransferase was high in young females, and adult males and females. Means of alkaline phosphatase was high in the adult males and females. The mean of total bilirubin was high in all groups, direct bilirubin was higher than normal in adult males and females. Means of indirect bilirubin were within normal, cholesterol values were within normal. total protein low in young females, globin level high in adult males albumin level was high in young males. In conclusion, ALT was high in young males, while AST was high in young females. ALT, AST ALP, and direct bilirubin were high in adult males, and females. Total bilirubin levels were high in all groups. indirect bilirubin, cholesterol was within normal. total protein low in young females, globin level high in adult males albumin level was high in young males.